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ADRC Researchers

Adam Wax Ph.D., M.A.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging

Affiliation: Duke

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Dr. Wax's research interests include optical spectroscopy for early cancer detection, novel microscopy and interferometry techniques.
Adrienne Aiken Morgan, PhD

Adrienne Aiken Morgan, Ph.D.

ADRC Interests: Geriatric Psychiatry

Affiliation: UNC-Chapel Hill

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My professional and research interests lie at the intersection of four broad areas of inquiry: sociocultural experience (e.g., race & ethnicity, education), cognition, aging, and health.
Adrienne Cox, PhD

Adrienne Cox, Ph.D.

ADRC Interests: Cell Biology - Cellular Aging

Affiliation: UNC-Chapel Hill

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Our lab is interested in molecular mechanisms of cancer biology, particularly concerning members of the Ras superfamily of proteins.

Albert La Spada M.D, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging

Affiliation: Duke

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Alexander Tropsha, Ph.D.

Alexander Tropsha, Ph.D.

ADRC Interests: Biomarkers

Affiliation: UNC-Chapel Hill

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Works in the fields of computational chemistry, cheminformatics and structural bioinformatics who works to develop new methodologies and software tools for computer-assisted drug design.

Alexandra Badea Ph.D.

ADRC Interests: Biomarkers, Clinical Aging Research, Neuroimaging

Affiliation: Duke

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Current Research interests: Alzheimer's Disease, Brain Imaging, MRI, Connectivity, Multivariate Biomarkers, Image Analysis, Neurological Conditions.
Alison Axtman, Ph.D.

Alison Axtman, Ph.D.

ADRC Interests: Biomarkers, Cell Biology - Immunology

Affiliation: UNC-Chapel Hill

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Axtman’s research has focused on the synthesis of small molecules that selectively modulate proteins implicated in disease-propagating pathways.
Allison E. Aiello, PhD

Allison Aiello, Ph.D.

Affiliation: UNC-Chapel Hill

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Research interests include: prevention of infectious diseases in the community setting; life course, infection, and chronic disease; genomics, aging, and immunity.
Amy Abramowitz, M.D.

Amy Abramowitz, M.D.

ADRC Interests: Clinical Aging Research, Geriatric Psychiatry

Affiliation: UNC-Chapel Hill

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Geriatric psychiatrist specializing in taking care of older adults with mental health and neurocognitive disorders.
Amy Gladfelter, Ph.D.

Amy Gladfelter, Ph.D.

ADRC Interests: Cell Biology - Cellular Aging

Affiliation: UNC-Chapel Hill

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We study how cytoplasm is spatially patterned and how cells sense their own shape.  We also investigate how timing in the cell division cycle can be highly variable yet still accurate.

Anatoli Yashin Ph.D., M.S.

ADRC Interests: Cell Biology - Cellular Aging

Affiliation: Duke

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Biodemography of Aging

Andrew West Ph.D.

ADRC Interests: Biomarkers, Cell Biology - Immunology

Affiliation: Duke

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The West lab focuses on identifying critical pathogenic mechanisms underlying neurological diseases like Parkinson’s disease with the goal of developing new therapeutics to block disease progression.

Anita Disney, Ph.D.

ADRC Interests: Neuropathology

Affiliation: Duke

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The primary goal of our research is to determine the role(s) that neuromodulators such as acetylcholine, noradrenaline, and serotonin oxytocin play in specifying functional connectivity across the wired circuitry of the brain, and how this dynamic circuit specification supports flexible behavior.

Anthony Sung, M.D.

ADRC Interests: Cell Biology - Cellular Aging, Clinical Trials

Affiliation: Duke

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Areas of interest include the role of the microbiota (the trillions of bacteria living in and on our bodies), nutrition, and exercise in modulating HCT outcomes such as graft-versus-host disease (GVHD) and infections.

Areniy Yashkin, Ph.D., MPH

ADRC Interests: Epidemiology & Population Health

Affiliation: Duke

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Ashley Price, Ph.D., MPH

ADRC Interests: Care Givers & Community Support, Epidemiology & Population Health

Affiliation: Duke

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Audrey Zhang, M.D.

Affiliation: Duke

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Internal Medicine Doctor, Primary Care Doctor, Resident

Bei Wu, Ph.D.

ADRC Interests: Care Givers & Community Support, Epidemiology & Population Health, Geriatric Psychiatry

Affiliation: Duke

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Research Interests: Aging and Global Health
Beverly H. Koller, PhD

Beverly Koller, Ph.D.

ADRC Interests: Cell Biology - Immunology

Affiliation: UNC-Chapel Hill

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Mouse models for human diseases, genes that modify disease progression

Bradley Goldstein, M.D, Ph.D.

ADRC Interests: Cell Biology - Cellular Aging

Affiliation: Duke

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The lab’s basic research program is broadly focused on understanding damage and repair in the peripheral olfactory system. Current projects seek to identify aging-related changes in human olfactory mucosa; to understand how certain epigenetic complexes regulate adult olfactory neurogenesis; and to understand post-viral olfactory losses.
Bryan Roth, MD, PhD

Bryan Roth, M.D, Ph.D.

ADRC Interests: Biomarkers

Affiliation: UNC-Chapel Hill

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GPCR structure and function, synthetic neurobiology, and drug discovery

Carl Pieper, DrPH

ADRC Interests: Epidemiology & Population Health

Affiliation: Duke

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Analytic Interests: Issues in the design of medical experiments and Issues in the analysis of repeated measures designs & longitudinal data.
Charlotte Boettiger, Ph.D.

Charlotte Boettiger, Ph.D.

ADRC Interests: Neuroimaging

Affiliation: UNC-Chapel Hill

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Work focuses on improving our understanding of the neurobiology of substance use disorders (SUDs) by identifying and characterizing neurocognitive biomarkers and intermediate phenotypes.

Chelsea Perfect, M.D., MPH

ADRC Interests: Geriatric Psychiatry

Affiliation: Duke

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Christine E Kistler, MD, MASc

Christine Kistler, M.D, MASc

ADRC Interests: Clinical Aging Research

Affiliation: UNC-Chapel Hill

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Dr. Kistler’s research includes Older adults, complex medical decision making, cancer screening, and hospice/palliative care
Clyde Hodge, Ph.D.

Clyde Hodge, Ph.D.

ADRC Interests: Biomarkers, Neuroimaging

Affiliation: UNC-Chapel Hill

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Our primary focus is on understanding how the positive reinforcing effects of drugs drive repetitive drug-seeking behavior and promote the transition from use to abuse.

Courtney Van Houtven, Ph.D.

ADRC Interests: Geriatric Psychiatry

Affiliation: Duke

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Dr. Van Houtven’s aging and economics research interests encompass long-term care financing, intra-household decision-making, informal care, and home- and community-based services. She examines how family caregiving affects health care utilization, expenditures, health and work outcomes of care recipients and caregivers. She is also interested in understanding how best to support family caregivers to optimize caregiver and care recipient outcomes.

Cristian Badea, Ph.D.

ADRC Interests: Biomarkers, Neuroimaging

Affiliation: Duke

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Spectral CT, Cardiac CT, Image Reconstruction, Deep Learning, Nanoparticles, Theranostics, Co-Clinical cancer trials, Small Animal Imaging
Cristine Henage, Ed.D

Cristine Henage, Ed.D.

ADRC Interests: Geriatric Psychiatry

Affiliation: UNC-Chapel Hill

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Assistant Director, Carolina Geriatric Education Center & Carolina Geriatric Workforce Enhancement Program

Daniel Saban, Ph.D., M.S.

ADRC Interests: Cell Biology - Immunology, Neuropathology

Affiliation: Duke

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Daniel Parker, M.D, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging, Clinical Aging Research

Affiliation: Duke

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biological aging, geroscience, geroprotection, caloric restriction, exercise training, Alzheimer's disease and related dementias, age-related cognitive impairment

David Lawrence, Ph.D.

ADRC Interests: Cell Biology - Immunology, Cell Biology - Cellular Aging

Affiliation: UNC-Chapel Hill

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Cancer detection and treatment and, to a more limited extent, inflammatory diseases.

David Murdoch, M.D.

ADRC Interests: Cell Biology - Immunology, Epidemiology & Population Health

Affiliation: Duke

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My research focuses on T cell immunology utilizing a variety of platforms including polychromatic flow cytometry, cytokine multiplexing, and novel single cell assays.

Deborah Rose, M.D.

ADRC Interests: Care Givers & Community Support, Epidemiology & Population Health

Affiliation: Duke

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My career research interests are in studying the role that adverse childhood experiences and chronic toxic stress play in the pathogenesis of AD, as well as contribute to the racial disparities seen in this condition.

Dennis Turner, M.D.

ADRC Interests: Clinical Trials

Affiliation: Duke

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Clinical trials in Parkinson disease, Alzheimer disease, translational research in Parkinson disease, tremor, stroke, and preclinical studies on Alzheimer's disease models, stroke, metabolism, and cerebral blood flow.

Dilraj Grewal, M.D.

ADRC Interests: Neuropathology

Affiliation: Duke

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Dilraj Grewal, MD specializes in the medical and surgical management of patients with complex Vitreoretinal pathology and Uveitis.

Donald McDonnell, Ph.D.

ADRC Interests: Biomarkers

Affiliation: Duke

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The research in our group is focused on the development and application of mechanism based approaches to identify novel therapeutics for use in the treatment and prevention of hormonally responsive cancers. Specifically we are interested in the pharmaceutical exploitation of the estrogen and androgen receptors as therapeutic targets in breast and prostate cancers and in defining how these receptors influence the pathogenesis of these diseases.

Dong Yan, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging

Affiliation: Duke

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We are interested in understanding the molecular mechanisms underlying neural circuit formation during development and degeneration in aging.
Donglin Zeng, PhD

Donglin Zeng, Ph.D.

Affiliation: UNC-Chapel Hill

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Personalized medicine, machine learning, biomarker discovery, clinical trials, electronic health records, semiparametirc modelling, survival analysis, high dimensional inference.
Douglas Cyr, PhD

Douglas Cyr, Ph.D.

ADRC Interests: Biomarkers, Cell Biology - Immunology, Genetics

Affiliation: UNC-Chapel Hill

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Focused on understanding the protein folding problem and defining cellular responses to proteotoxic stress. A central focus is understanding how Hsp70 molecular chaperones mediate protein triage and determine the fate of misfolded proteins.

Eleanor Schildwachter McConnell, Ph.D.

ADRC Interests: Geriatric Psychiatry

Affiliation: Duke

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Dr. McConnell's program of research focuses on factors that influence functional decline in very frail older adults. Her academic interests include frailty in the aged, the role of the environment in promoting function, and the conduct and testing of nursing interventions to prevent decline in those with chronic illness.

Elijah Lackey, M.D.

Affiliation: Duke

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Elizabeth Hauser, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Immunology, Cell Biology - Cellular Aging, Genetics

Affiliation: Duke

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My research interests are focused on developing and applying statistical methods to search for genes causing common human diseases. Recent work has been in the development of statistical methods for genetic studies and in identifying optimal study designs for genetic studies of complex traits.
Emily Cetrone, MD

Emily Cetrone, M.D.

ADRC Interests: Clinical Aging Research

Affiliation: UNC-Chapel Hill

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Geriatric primary care, medical education, dementia, caregiver stress
Eran Dayan, Ph.D.

Eran Dayan, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration

Affiliation: UNC-Chapel Hill

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Our lab studies neurodegeneration in the human brain using data science and informatics approaches. We seek to identify the fundamental properties of brain organization and reorganization occurring due to neurodegenerative diseases, and develop methods and tools that can eventually be used for diagnostic and prognostic purposes.
Eric A. Whitsel, MD, MPH

Eric Whitsel, M.D, MPH

Affiliation: UNC-Chapel Hill

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Electrocardiography, CVD Surveillance, Environmental Epidemiology, and Genetics & Epigenetics

Fan Wang, Ph.D.

ADRC Interests: Genetics, Neuropathology

Affiliation: Duke

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My lab studies neural circuit basis of sensory perception. Specifically we are interested in determining neural circuits underlying (1) active touch sensation including tactile processing stream and motor control of touch sensors on the face; (2) pain sensation including both sensory-discriminative and affective aspects of pain; and (3) general anesthesia including the active pain-suppression process.
Fei Zou, PhD

Fei Zou, Ph.D.

ADRC Interests: Genetics

Affiliation: UNC-Chapel Hill

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Dr. Zou’s research interests lie in the development and examination of the theoretical methodologies and statistical properties appropriate for the interpretation of genetic data. Her current research focuses on developing machine learning algorithms, such as deep learning, for big EHR data and high-dimensional genetic and genomic data.
Frances Potjewyd, Ph.D.

Frances Potjewdy, Ph.D.

Affiliation: UNC-Chapel Hill

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Fred Jarskog, M.D, Ph.D.

Affiliation: UNC-Chapel Hill

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Research is focused on the pathophysiology and treatment of schizophrenia. Dr. Jarskog has studied the potential efficacy of drugs with novel mechanisms of action, with a particular focus on neuroprotective mechanisms, to enhance standard antipsychotic therapies.

Fulton Crews, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration

Affiliation: UNC-Chapel Hill

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Mental disease, including addiction and neurodegeneration

Gerardo Heiss, Ph.D.

Affiliation: UNC-Chapel Hill

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Research include noninvasive measures of vascular disease in populations; genetic and environmental determinants of atherosclerosis; inflammatory precursors of diabetes and heart disease; cardiovascular health of women and minority populations; mechanisms relating socio-economic status to cardiovascular health and successful aging, and applications of electronic health records in population research.

Giselle Lopez, M.D, Ph.D.

ADRC Interests: Neuropathology

Affiliation: Duke

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I am a physician scientist with a clinical focus on neuropathology, and a research interest in brain tumors.

Glenn Matsushima, Ph.D.

ADRC Interests: Cell Biology - Immunology

Affiliation: UNC-Chapel Hill

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Our laboratory is interested primarily in the responses of macrophages during injury to the central nervous system and during inflammation after insult by bacterial pathogens. We use molecular, cellular and biochemical approaches both in vitro and in vivo to identify the function of key mediators during pathogenesis.

Graham Diering, Ph.D.

ADRC Interests: Genetics

Affiliation: UNC-Chapel Hill

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Researches the use of methods in biochemistry, proteomics, cell biology, and animal behavior to understand brain function and how disruptions in brain function contribute to cognitive disorders.

Guorong Wu, Ph.D.

ADRC Interests: Biomarkers

Affiliation: UNC-Chapel Hill

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Interested in discovering biomarkers across neuro-diseases, exploring how variations in the genome change the structure and development of the brain, and establishing neuro-biological basis to visualize the pathophysiological mechanisms of neuro-diseases using data-driven approach.
Gwenn Garden, MD, PhD

Gwenn Garden, M.D, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging, Neuropathology

Affiliation: UNC-Chapel Hill

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Clinical Interests - Neuroinflammation, neurodegeneration and dementia Research Interests - Molecular pathogenesis of neurodegenerative disorders and the basic cellular biology of inflammation in the central nervous system

Haichen Wang, M.D.

ADRC Interests: Cell Biology - Neurodegeneration, Neuroimaging

Affiliation: Duke

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Han Zhang Ph.D.

ADRC Interests: Cell Biology - Cellular Aging, Neuroimaging

Affiliation: UNC-Chapel Hill

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Research focuses on developing new functional image analysis methods of large longitudinal data for early brain development (birth to age 6).

Hanzhang Xu, Ph.D.

ADRC Interests: Epidemiology & Population Health, Geriatric Psychiatry

Affiliation: Duke

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My current program of research falls under two themes: (i) the analysis of health disparities in a multinational context, with a particular focus on the cognitive function among older adults; and (ii) the integration of patient-reported social factors in cardiovascular outcome research.
Heather Whitson, MD

Heather Whitson, M.D.

ADRC Interests: Geriatric Psychiatry, Neuropathology

Affiliation: Duke

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Research is focused on improving care options and resilience for people with multiple chronic conditions.

Heidi White, M.D.

ADRC Interests: Care Givers & Community Support, Geriatric Psychiatry

Affiliation: Duke

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Dr. White's clinical expertise involves the care of older adults, especially care transitions, long-term care, and post-acute care. Current work includes studying the effects of personalized music in older adults with dementia and implementing personalized music programs for pain and delirium relief in hospital and dementia care in nursing homes and assisted living facilities.

Henry Tseng, M.D, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Neuropathology

Affiliation: Duke

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Dr. Tseng's research investigates molecular and cellular functions of optineurin, which is a gene associated with glaucoma, brain neurodegeneration, and Paget's disease of the bone.

Hiroaki Matsunami, Ph.D.

ADRC Interests: Genetics, Neuropathology

Affiliation: Duke

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We are interested in the molecular mechanisms underlying chemosensation (taste and smell) in mammals. The receptors that detect odorants, pheromones, and many tastants including bitter and sweet chemicals are G-protein coupled receptors (GPCRs), which typically have seven transmembrane domains.

Hongtu Zhu, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Neuroimaging

Affiliation: UNC-Chapel Hill

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Studying aging and child development through statistics, biostatistics, medical imaging, genetics and computational neuroscience, and neuroimaging data analysis.

Igor Akushevich, Ph.D.

ADRC Interests: Care Givers & Community Support, Epidemiology & Population Health

Affiliation: Duke

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James White, Ph.D., M.S.

ADRC Interests: Biomarkers, Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging, Clinical Aging Research

Affiliation: Duke

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Jamie Capal, M.D.

ADRC Interests: Cell Biology - Cellular Aging, Genetics

Affiliation: UNC-Chapel Hill

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Research focus on neurodevelopmental conditions across the lifespan. I am developing a multi-disciplinary, comprehensive program of translational research around detection (particularly early detection) and multi-modal interventions (including pharmacotherapeutics, cognitive-behavioral therapies, and community support and services).

Jason Franz, Ph.D.

ADRC Interests: Geriatric Psychiatry

Affiliation: UNC-Chapel Hill

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Neuromuscular biomechanics; Sensorimotor control; Aging and age-related mobility impairment

Jason Surratt, Ph.D.

Affiliation: UNC-Chapel Hill

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Utilizes advanced mass spectrometry and chromatographic techniques to understand as deeply as possible the atmospheric chemistry that occurs in both the gas and particulate phases, with special focus on the chemistry leading to the formation of secondary organic aerosol (SOA).

Jeffrey Guptill, M.D.

ADRC Interests: Biomarkers, Clinical Aging Research, Clinical Trials, Neuropathology

Affiliation: Duke

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Jen-Tsan Chi, M.D, Ph.D.

ADRC Interests: Biomarkers, Cell Biology - Immunology, Genetics

Affiliation: Duke

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Current research interests: a) the genetic determinants and disease relevance of ferroptosis; b)a new stress pathway - mammalian stress response; c) genomic and single cell RNA analysis of red blood cells

John Batsis, M.D.

ADRC Interests: Geriatric Psychiatry

Affiliation: UNC-Chapel Hill

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Clinical: Geriatric Medicine, Obesity, Health Promotion, Frailty Research: Obesity and Physical Function in Older Adults; Using technology (telemedicine, remote monitoring) to enhance health in older adults

John Buse, M.D, Ph.D.

Affiliation: UNC-Chapel Hill

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Prevention and treatment of type 1 diabetes, type 2 diabetes and their complications.

Joshua Niznik, PharmD, Ph.D.

ADRC Interests: Genetics, Geriatric Psychiatry

Affiliation: UNC-Chapel Hill

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Clinical pharmacy; pharmacoepidemiology; Geriatrics; health services research; Medicare administrative data; polypharmacy; deprescribing chronic medications that may no longer have value for patients

Juan Song, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Immunology, Cell Biology - Cellular Aging

Affiliation: UNC-Chapel Hill

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Adult neurogenesis function and regulation

Jui-Heng Tseng, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Neuroimaging, Neuropathology

Affiliation: UNC-Chapel Hill

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Research focuses on post-translational modification of tau protein and its role in different stages of neurodegenerative diseases and lifespan.

Juliessa Pavon, M.D.

ADRC Interests: Epidemiology & Population Health, Geriatric Psychiatry

Affiliation: Duke

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Aging; data science; hospital care; older people; medical informatics; digital health; physical functions and mobility; polypharmacy.

Justine Seidenfeld, M.D.

ADRC Interests: Geriatric Psychiatry

Affiliation: Duke

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Emergency medicine; clinical science

Kari North, Ph.D.

ADRC Interests: Genetics

Affiliation: UNC-Chapel Hill

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Cardiovascular disease and associated risk factors.

Katie Meyer, ScD

Affiliation: UNC-Chapel Hill

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Nutritional and cardiovascular disease epidemiologist.

Kelly Giovanello, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging, Neuroimaging

Affiliation: UNC-Chapel Hill

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Primary research focus is to specify the cognitive processes and neural mechanisms mediating relational memory – the form of memory which represents relationships among items or informational elements.

Kelly Parsons, Ph.D.

ADRC Interests: Cell Biology - Immunology

Affiliation: UNC-Chapel Hill

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Director of technology commercialization at UNC Innovate Carolina.

Kevin Guskiewicz, Ph.D., ATC

ADRC Interests: Biomarkers, Cell Biology - Neurodegeneration

Affiliation: UNC-Chapel Hill

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UNC-Chapel Hill Chancellor Research focuses on the assessment of sport-related concussion and the long-term effects of concussion.

William Kirby Gottschalk, Ph.D.

ADRC Interests: Biomarkers, Cell Biology - Immunology, Clinical Aging Research

Affiliation: Duke

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Kirk Wilhelmsen, M.D, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration

Affiliation: UNC-Chapel Hill

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Genetic mapping of susceptibility loci for complex traits and the positional cloning of genes responsible for neurodegenerative disorders.

Kristal Riska, Ph.D.

ADRC Interests: Neuropathology

Affiliation: Duke

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Laura Porter, Ph.D.

ADRC Interests: Care Givers & Community Support

Affiliation: Duke

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My research focuses on developing and evaluating behavioral interventions to help patients and their family members cope with the symptoms and psychological demands associated with chronic and life-limiting illness.

Laura Previll, M.D, MPH

ADRC Interests: Care Givers & Community Support, Epidemiology & Population Health

Affiliation: Duke

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Laura Raffield, Ph.D.

ADRC Interests: Genetics

Affiliation: UNC-Chapel Hill

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Genetic epidemiology, human genetics, genome-wide association studies, precision medicine, multi-omics, cardiovascular disease, Alzheimer’s disease and related dementias, hemostasis, inflammation, hematological traits.

Laurie Sanders, Ph.D.

ADRC Interests: Biomarkers, Cell Biology - Neurodegeneration, Cell Biology - Immunology, Cell Biology - Cellular Aging, Genetics

Affiliation: Duke

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Leon Coleman, M.D, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Immunology

Affiliation: UNC-Chapel Hill

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Neuroimmune signaling in alcohol use disorders and peripheral immune dysfunction in systemic inflammatory disease.

Lisa Gwyther, M.S.W

ADRC Interests: Geriatric Psychiatry

Affiliation: Duke

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Current research interests: Alzheimer's disease nursing home and assisted living care, community translation of evidence-based dementia caregiver interventions, early stage Alzheimer's programming, non-pharmacological approaches to dementia-related behavioral symptoms.

Luke Bartelt

Affiliation: Duke

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Basic Science student

Marc Niethammer, Ph.D.

ADRC Interests: Neuroimaging

Affiliation: UNC-Chapel Hill

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Medical image analysis; shape analysis, image segmentation, deformable registration, image-based estimation methods.

Mari Shinohara, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Immunology

Affiliation: Duke

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In my lab, we use mouse models for infectious and autoimmune diseases to understand the cellular and molecular mechanisms of; pathogen recognition by PRRs in macrophages and DCs, initiation of inflammatory responses in the innate immune system, and the impact of innate immune inflammation on the development and regulation of T cell-mediated adaptive immune responses.

Mark Tommerdahl, Ph.D., M.S.

ADRC Interests: Neuroimaging

Affiliation: UNC-Chapel Hill

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Somatosensory Cortical Dynamics, and Neurocomputation in Living Neural Networks

Martin Styner, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Neuroimaging, Neuropathology

Affiliation: UNC-Chapel Hill

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Background in diffusion tensor imaging, anatomical structure and tissue segmentation, structural brain morphometry, modeling, deformable registration, atlas building.

Marvin Swartz, M.D.

ADRC Interests: Care Givers & Community Support, Epidemiology & Population Health, Geriatric Psychiatry

Affiliation: Duke

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My major research interest is in examining the effectiveness of services for severely mentally ill individuals, including factors that improve or impede good outcomes. Current research includes: the effectiveness of involuntary outpatient commitment, psychiatric advance directives, criminal justice outcomes for persons with mental illnesses, violence and mental illness and antipsychotic medications.

Matt Scaglione, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging, Clinical Aging Research

Affiliation: Duke

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The Scaglione lab is interested in the regulation of protein homeostasis (proteostasis) in neurodegenerative diseases. We use a wide array of model systems including protein biochemistry, the social amoeba Dictyostelium discoideum , human cell culture, and mouse models to understand cellular pathways that deal with misfolded proteins.

Matthew Harris, Ph.D., ABPP

ADRC Interests: Neuropathology

Affiliation: UNC-Chapel Hill

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Neurological illness and injury, traumatic brain injury, dementia, cognition in epilepsy and epilepsy surgery.

Matthew Maciejewski, Ph.D.

ADRC Interests: Epidemiology & Population Health

Affiliation: Duke, UNC-Chapel Hill

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Areas of expertise: Health Services Research, Health Economics, Health Policy, Multimorbidity

Melissa Harris, Ph.D., RN

ADRC Interests: Care Givers & Community Support, Geriatric Psychiatry

Affiliation: Duke

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Her research focuses broadly on the quality of life and care of older adults living with dementia and their families. More specifically, she focuses on non-pharmacologic interventions to help reduce stress experienced by people living with dementia.

Michael Devinney, M.D, Ph.D.

ADRC Interests: Cell Biology - Immunology, Clinical Trials, Geriatric Psychiatry

Affiliation: Duke

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Delirium and cognitive dysfunction following surgery are associated with significant long-term risk for dementia, diminished quality of life, and increased mortality. To better understand the relationship between OSA, postoperative neurocognitive disorders and neuroinflammation, we are carrying out a prospective observational cohort study called Sleep Apnea, Neuroinflammation, and cognitive Dysfunction Manifesting After Non-cardiac surgery (SANDMAN).

Michelle Meyer, Ph.D., MPH

Affiliation: UNC-Chapel Hill

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Cardiovascular Epidemiology, Women's Health

Mike Hauser, Ph.D.

ADRC Interests: Biomarkers, Genetics, Neuropathology

Affiliation: Duke

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Ocular genetics and age related macular degeneration.

Milta Little, D.O.

ADRC Interests: Clinical Trials, Geriatric Psychiatry

Affiliation: Duke

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Shivanand Lad, M.D, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging, Clinical Trials

Affiliation: Duke

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Neuromodulation; Neurorestoration; Bioengineering; Medical Device Design; Clinical Trials; Data Science; Health Outcomes.

Nathan Walker, M.D.

ADRC Interests: Neuropathology

Affiliation: UNC-Chapel Hill

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The interplay of sleep and neurodegenerative disorders.

Patrick J. Eric Stallard

ADRC Interests: Epidemiology & Population Health, Genetics

Affiliation: Duke

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My research expertise includes modeling and forecasting for biomedical demography and health/LTC actuarial practice.
Peggye Dilworth-Anderson, PhD

Peggye Dilworth-Anderson, Ph.D.

Affiliation: UNC-Chapel Hill

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Research focuses on Health Disparities, Dementia and Caregiving, Family Caregiving and Aging, and Minority Aging & Aging in Cultural Context

Pew-Thian Yap, Ph.D.

ADRC Interests: Neuroimaging

Affiliation: UNC-Chapel Hill

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Leads a wide range of research projects spanning image acquisition, reconstruction, quality control, processing, and analysis, with applications to neuroscience, radiomics, and surgical planning.

Philip Sloane, M.D, MPH CS

ADRC Interests: Geriatric Psychiatry, Neuropathology

Affiliation: UNC-Chapel Hill

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Research interests include institutional and community-based long-term care, management of Alzheimer’s disease and related dementias, medical care of older persons, medical symptoms, and translational research.

Qisheng Zhang, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Immunology, Neuropathology

Affiliation: UNC-Chapel Hill

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Studies signaling pathways that are involved in development and disease by developing novel chemical probes and technologies.

Rick Meeker, Ph.D.

ADRC Interests: Neuropathology

Affiliation: UNC-Chapel Hill

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Brain cholinergic receptors, vasopressin, AIDS research, HIV and FIV

Ryan Vetreno, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Immunology

Affiliation: UNC-Chapel Hill

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Focuses on the investigation of proinflammatory neuroimmune and epigenetic mechanisms in animal models of developmental neurobiology and neurodegeneration, including (1) alcohol pharmacology, (2) adolescent neurodevelopment, (3) cholinergic system and neurocircuitry, and (4) Alzheimer’s disease

Sandra Mooney, Ph.D.

Affiliation: UNC-Chapel Hill

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Uses animal models to test nutritional interventions that may ameliorate alcohol-induced deficits as well as examining other factors, such as genes and nutrition, that confer vulnerability or resistance.

Sarah Cohen, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration

Affiliation: UNC-Chapel Hill

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Microscopy techniques used to understand how defects in lipid trafficking contribute to metabolic and neurodegenerative disease.

Sheryl Moy, Ph.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging, Clinical Aging Research, Genetics, Neuropathology

Affiliation: UNC-Chapel Hill

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Genetic and environmental factors in susceptibility to neurodevelopmental disorders, and preclinical efficacy testing with novel therapeutic agents, using mouse models for psychiatric and neurological conditions.

Sheryl Zimmerman, Ph.D., MSW

ADRC Interests: Geriatric Psychiatry

Affiliation: UNC-Chapel Hill

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Co-Director, Program on Aging, Disability, and Long-Term Care, Cecil G. Sheps Center for Health Services Research; and Director of Aging Research, School of Social Work

Susan Gaylord, Ph.D.

ADRC Interests: Geriatric Psychiatry

Affiliation: UNC-Chapel Hill

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Alternative and complementary therapy education; Health beliefs; Mindfulness meditation; Homeopathy; Spirituality; Gerontology; Women’s health issues

Sylvia Fitting, Ph.D.

ADRC Interests: Cell Biology - Immunology, Neuropathology

Affiliation: UNC-Chapel Hill

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Cellular, functional, and behavioral mechanisms of the neurotoxic consequences of HIV-1 protein on the central nervous system and the role of the (endo)cannabinoid system

Thomas Kash, Ph.D.

ADRC Interests: Neuropathology

Affiliation: UNC-Chapel Hill

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Synaptic Transmission and Plasticity; Identification of neuronal substrates that underlie alcohol and drug abuse induced behaviors; and Determining the impact of stress on neuronal circuitry important for emotional behavior.

Timothy Elston, Ph.D.

ADRC Interests: Biomarkers, Cell Biology - Immunology, Neuroimaging

Affiliation: UNC-Chapel Hill

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My lab integrates computational approaches, including mathematical modeling and quantitative image analysis, with experimental investigations to understand complex cellular behavior.

Vivian Go, Ph.D.

Affiliation: UNC-Chapel Hill

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Research focuses on the intersection between HIV and co-morbidities including mental health and opioid use disorders, stigma and discrimination among key populations including people who inject drugs and men who have sex with men, and scaling up evidence-based HIV interventions.

Wei-Tang Chang, Ph.D.

ADRC Interests: Neuroimaging

Affiliation: UNC-Chapel Hill

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Developments and applications of ultrahigh-resolution functional and diffusion MRI, robust image reconstruction, brain connectivity analysis.

William Snider, M.D.

ADRC Interests: Cell Biology - Neurodegeneration, Cell Biology - Cellular Aging, Neuropathology

Affiliation: UNC-Chapel Hill

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Research is directed at biological actions of neuronal growth factors and signaling mechanisms downstream of receptor tyrosine kinases.

Yang Claire Yang, Ph.D., M.S.

ADRC Interests: Neuropathology

Affiliation: UNC-Chapel Hill

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Focused on health disparities, social disparities in health, and causes of health differences.