Data Resource Library

The Duke/UNC ADRC oversees two cohorts, the Memory & Aging Study (MAS) (n=420 over five years) and the Young Cohort (n=120). Participants from both cohorts are recruited from the Triangle and Eastern North Carolina.

The Duke University School of Medicine, Department of Neurology collects cerebrospinal fluid and plasma from patients in the Memory Disorders Clinic along with basic demographic and clinical data. These biospecimens are available to all researchers. We ask that all researchers submit a 1 page summary of the project before receiving biospecimens and acknowledgement of the use of this biorepository on all publications.

Recognized as a premier biorepository for Alzheimer’s disease research, the Bryan Brain Bank and Biorepository provides investigators worldwide with access to longitudinal clinical data, high quality biospecimens, and histology services to support and advance basic and clinical research.

The Duke/UNC ADRC oversees the Memory & Cognitive Health Study, a sub-study of the MURDOCK Community Registry and Biorepository. The parent study was a longitudinal cohort recruited from a 20-Zip Code region in the Southeastern United States (U.S.) that is centered in the city of Kannapolis, NC and encompasses Cabarrus County, NC.

The PORT lab is interested in perioperative neurocognitive disorders, as well as mechanisms by which the APOE4 allele leads to long term neurocognitive decline. Available data includes samples from approximately 600 subjects collected before, during and after surgery. Data collected includes demographics, cognitive testing, and delirium screening, and samples of blood, plasma, and CSF supernatant and CSF cell pellets. Some subjects also have: fMRI data, intra-op EEG. Samples are stored in MSRB3.