Home » News Update – June 3

    News Update – June 3

    Nine out of ten U.S. neurologists have Aduhelm efficacy doubts

    Recent article out in Drug Discovery & Development quotes our Internal Advisory Committee Chair, Dr. Doraiswamy

    By Brian Buntz

    A recent physician survey found that 89% of neurologists in the U.S. have concerns about the efficacy of the controversial Alzheimer’s drug Aduhelm (aducanumab) from Biogen and Eisai Co.  Nearly as many — 87% — were concerned about the drug’s safety profile.  The survey from the physician social media network Sermo (New York City) asked more than 50 neurologists about their view of the drug, which has failed to find widespread use, generating just $3 million in 2021. Only 11% of the neurologists surveyed reported prescribing the drug.

    Read more >

    An integrated genome and phenome-wide association study approach to understanding Alzheimer’s disease predisposition

    Duke/UNC ADRC Research Education Component Core lead, Dr. Kyle Walsh, and first author Archita Khaire, have a newly accepted manuscript in-press at Neurobiology of Aging. Congratulations to you both on this important work! 

    Genome-wide association studies (GWAS) have identified common single nucleotide polymorphisms (SNPs) that increase late-onset Alzheimer’s disease (LOAD) risk.

    Read more >


     DoD Congressionally Directed Medical Research Program (CDMRP) Peer Reviewed Alzheimer’s Research Program

    Upcoming opportunities through DoD’s Congressionally Directed Medical Research Program Peer Reviewed Alzheimer’s Research Program:

    • Accelerating Diagnostics Research Award
    • Investigator-Initiated Research Award

    Letters of Intent due June 17th

    Duke investigators who plan to apply should contact Chris Erlien in Office of Research Development (christine.erlien@duke.edu)


    Alzheimer’s Association International Conference

    July 31 – August 4, San Diego and Online

    Join us in San Diego and online for AAIC 2022, where the world’s leading basic scientists, clinical researchers, early career investigators, clinicians and the care research community will share breaking research discoveries that will lead to methods of prevention and treatment and improvements in diagnosis for Alzheimer’s disease. Register >

    • Please let us know if you are attending the conference. We would like to plan a fun gathering and need a head count. Also let us know if you have an accepted abstract(s). Please contact michelle.cooley@duke.edu.



    June 24, 5 pm – 7 pm & June 25, 9 am – 4:15 pm
    Symposium for Learning about Alzheimer’s disease-related Medical research at Duke and UNC (SLAM-DUNC)
    Duke Karsh Alumni and Visitors Center
    Open to researchers, clinicians, and trainees from Duke, UNC, NCCU, UNC-Pembroke, and ECU
    Learn More

    July 28, 4pm – 5pm
    ADRD IDEAS Forum
    “The Role of Selected Natural Products in Triggering the Autophagy-Lysosomal Pathway to Promote Brain Health”
    Michael Fernandes de Almeida, M.S.
    Research Specialist
    Biotechnology Research and Training Center
    University of North Carolina – Pembroke
    Join Zoom Meeting

    July 31 – August 4, San Diego and online
    Alzheimer’s Association International Conference (AAIC)
    Let us know if you will be attending and/or have an accepted abstract.
    Register >

    September 21, 5:30-6 pm reception; 6 – 7 pm lecture
    Karen L. Wrenn Lectureship: “On the Occasion of World Alzheimer’s Day”
    Bryan Research Building, Room 103, 311 Research Drive, Durham, NC, Parking TBA
    Host: Murali Doraiswamy, MBBS