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News Update – June 3

Nine out of ten U.S. neurologists have Aduhelm efficacy doubts

Recent article out in Drug Discovery & Development quotes our Internal Advisory Committee Chair, Dr. Doraiswamy

By Brian Buntz

A recent physician survey found that 89% of neurologists in the U.S. have concerns about the efficacy of the controversial Alzheimer’s drug Aduhelm (aducanumab) from Biogen and Eisai Co.  Nearly as many — 87% — were concerned about the drug’s safety profile.  The survey from the physician social media network Sermo (New York City) asked more than 50 neurologists about their view of the drug, which has failed to find widespread use, generating just $3 million in 2021. Only 11% of the neurologists surveyed reported prescribing the drug.

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An integrated genome and phenome-wide association study approach to understanding Alzheimer’s disease predisposition

Duke/UNC ADRC Research Education Component Core lead, Dr. Kyle Walsh, and first author Archita Khaire, have a newly accepted manuscript in-press at Neurobiology of Aging. Congratulations to you both on this important work! 

Genome-wide association studies (GWAS) have identified common single nucleotide polymorphisms (SNPs) that increase late-onset Alzheimer’s disease (LOAD) risk.

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 DoD Congressionally Directed Medical Research Program (CDMRP) Peer Reviewed Alzheimer’s Research Program

Upcoming opportunities through DoD’s Congressionally Directed Medical Research Program Peer Reviewed Alzheimer’s Research Program:

  • Accelerating Diagnostics Research Award
  • Investigator-Initiated Research Award

Letters of Intent due June 17th

Duke investigators who plan to apply should contact Chris Erlien in Office of Research Development (christine.erlien@duke.edu)

 


Alzheimer’s Association International Conference

July 31 – August 4, San Diego and Online

Join us in San Diego and online for AAIC 2022, where the world’s leading basic scientists, clinical researchers, early career investigators, clinicians and the care research community will share breaking research discoveries that will lead to methods of prevention and treatment and improvements in diagnosis for Alzheimer’s disease. Register >

  • Please let us know if you are attending the conference. We would like to plan a fun gathering and need a head count. Also let us know if you have an accepted abstract(s). Please contact michelle.cooley@duke.edu.

 


Calendar

June 24, 5 pm – 7 pm & June 25, 9 am – 4:15 pm
Symposium for Learning about Alzheimer’s disease-related Medical research at Duke and UNC (SLAM-DUNC)
Duke Karsh Alumni and Visitors Center
Open to researchers, clinicians, and trainees from Duke, UNC, NCCU, UNC-Pembroke, and ECU
Learn More

July 28, 4pm – 5pm
ADRD IDEAS Forum
“The Role of Selected Natural Products in Triggering the Autophagy-Lysosomal Pathway to Promote Brain Health”
Michael Fernandes de Almeida, M.S.
Research Specialist
Biotechnology Research and Training Center
University of North Carolina – Pembroke
Join Zoom Meeting

July 31 – August 4, San Diego and online
Alzheimer’s Association International Conference (AAIC)
Let us know if you will be attending and/or have an accepted abstract.
Register >

September 21, 5:30-6 pm reception; 6 – 7 pm lecture
Karen L. Wrenn Lectureship: “On the Occasion of World Alzheimer’s Day”
Bryan Research Building, Room 103, 311 Research Drive, Durham, NC, Parking TBA
Host: Murali Doraiswamy, MBBS