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ADRC Affiliated Researchers

Jamie Capal, M.D.

UNC-Chapel Hill
Biomarkers
Clinical Trials
Genetics
Research interests include studying neurodevelopmental disorders across the lifespan, including Down syndrome, Fragile X syndrome, Angelman syndrome, and Tuberous Sclerosis Complex, and the relationship between early neurodevelopmental conditions and later neurodegeneration.

Avshalom Caspi, M.A., Ph.D.

Duke University
Epidemiology & Population Health
Genetics
Geriatric Psychiatry
1) How do childhood experiences shape aging and the course of health inequalities across the life span? (2) How do genetic differences between people shape the way they respond to their environments? (3) What are the best ways to assess and measure personality differences between people?

Emily Cetrone, M.D.

UNC-Chapel Hill
Geriatric primary care, medical education, dementia, caregiver stress

Wei-Tang Chang, Ph.D.

UNC-Chapel Hill
Developments and applications of ultrahigh-resolution functional and diffusion MRI, robust image reconstruction, brain connectivity analysis.

Marianne Chanti-Ketterl, PhD, MSPH

Assistant Professor in Psychiatry and Behavioral Sciences

Duke University
Care Givers & Community Support
Dementia Care
Epidemiology & Population Health

Xian Chen, PhD

UNC-Chapel Hill
Biomarkers
Our lab focuses on both developments and applications of cutting-edge technologies of proteomics and proteogenomics for mechanistic elucidation and biomarker discovery in AD and ADRD.

Pratik Chhatbar, Ph.D.

Duke University
Neuromodulation / Neuroprosthetics / Upcoming technologies

Jen-Tsan Chi, M.D, Ph.D.

Duke University
Biomarkers
Genetics
Current research interests: a) the genetic determinants and disease relevance of ferroptosis; b)a new stress pathway – mammalian stress response; c) genomic and single cell RNA analysis of red blood cells

Ornit Chiba-Falek, Ph.D.

Duke University
Alzheimer’s Disease
Neurodegeneration
Our research attempts to better understand the genetic processes underpinning age-related neurodegenerative diseases, in particular Alzheimer’s disease, related dementia, and Lewy body spectrum disorders.

Sandra J. Cobb, PhD, MSN, FNP-C, RN

Neurology Nurse Practitioner & Team Clinician for Study Visits

Duke University
Alzheimer’s Disease
Care Givers & Community Support
Dementia Care
I take care of patients with neurodegenerative disorders that impair memory and thinking, such as Alzheimer’s disease, Lewy body dementia, and frontotemporal dementia. My goal is to find interventions that work best for maintaining quality of life for patients and caregivers.

Sarah Cohen, Ph.D.

UNC-Chapel Hill
Neurodegeneration
Dr. Cohen uses state-of-the-art microscopy techniques to study organelle dynamics and lipid metabolism in the context of neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, and Amyotrophic lateral sclerosis (ALS). Keywords: cell biology; organelles; lipids; Alzheimer’s disease; APOE

Todd Cohen, Ph.D.

Associate Professor – Neuroscience Research

UNC-Chapel Hill
Biomarkers
1. Alzheimer’s disease, frontotemporal dementia, amyotrophic lateral sclerosis 2. Protein aggregation mechanisms, post-translational modifications, reversible acetylation mediated by HATs and HDACs

Leon Coleman, M.D, Ph.D.

UNC-Chapel Hill
Animal Models
Behavioral Pathology
Cellular Pathology
The Coleman lab studies how modifiable risk factors for AD promote its cellular and behavioral pathology. By using mouse models and human tissue, we attempt to identify novel diagnostic and therapeutic targets for AD. Studies focus on underlying cellular and molecular pathology that promote AD pathogenesis and progression

Carol Colton, Ph.D.

Professor in Neurology

Duke University
Cell Biology – Cellular Aging
Cell Biology – Immunology
Cell Biology – Neurodegeneration
Clinical Aging Research
Recent research has focused on the regulation of microglial reactive oxygen species and reactive nitrogen species production as well as other cytoactive macrophage products that are made during the classical and alternative activation states associated with chronic neurodegeneration.

Fulton Crews, Ph.D.

UNC-Chapel Hill
Mental disease, including addiction and neurodegeneration

Douglas Cyr, Ph.D.

UNC-Chapel Hill
Biomarkers
Genetics
Focused on understanding the protein folding problem and defining cellular responses to proteotoxic stress. A central focus is understanding how Hsp70 molecular chaperones mediate protein triage and determine the fate of misfolded proteins.

Simon Davis, Ph.D.

Duke University
The primary focus of work in our lab is investigating white matter changes in the aging brain, examining how knowledge supports long-term memory functioning, and probing the effects of brain stimulation on age-related memory loss.

Eran Dayan, Ph.D.

UNC-Chapel Hill
Biomarkers
Our lab studies neurodegeneration in the human brain using data science and informatics approaches. We seek to identify the fundamental properties of brain organization and reorganization occurring due to neurodegenerative diseases, and develop methods and tools that can eventually be used for diagnostic and prognostic purposes.

Michael Devinney, M.D, Ph.D.

Associate Core Leader

Duke University
Clinical Trials
Delirium and cognitive dysfunction following surgery are associated with significant long-term risk for dementia, diminished quality of life, and increased mortality. To better understand the relationship between OSA, postoperative neurocognitive disorders and neuroinflammation, we are carrying out a prospective observational cohort study called Sleep Apnea, Neuroinflammation, and cognitive Dysfunction Manifesting After Non-cardiac surgery (SANDMAN).

Yarui Diao, Ph.D.

Duke University
Gene regulation in tissue regeneration and tumorigenesis
Study Participants Researchers Family & Patient Alzheimer’s Resources
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