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ADRC Cores

The Duke-UNC Alzheimer’s Disease Research Collaborative (ADRC) is comprised of seven collaborative groups, or “cores.” The administrative core provides coordination as well as scientific and administrative leadership to ensure operational efficiency, fiscal responsibility, and regulatory compliance. The Administrative Core also oversees the Developmental Project program.

The other six cores include the following:

Biomarker Core

Biomarker Core

The Biomarker Core’s objective is to acquire and analyze biofluid and imaging biomarkers; characterize their relevance to AD+ADRD, and determine the underlying age-related factors that drive the development, progression, or experience of the disease; and to advise local investigators in AD+ADRD biomarker research

Clinical Care Core

Clinical Core

The Clinical Core is responsible for recruiting, clinically characterizing, and following a diverse group of participants who will provide biomarker data and brain tissue to investigators studying AD+ADRD.

Data Management and Statistics Core

Data Management and Statistics Core

The Data Management and Statistics Core offers integrated data management and statistical/ bioinformatics collaborative expertise. DMS consultation is available to all development project awardees.

Neuropathology Core

Neuropathology Core

The Neuropathology Core supports research by performing postmortem histopathological analysis and providing well-annotated and high-quality postmortem tissue and biofluids to investigators studying AD+ADRD.

Outreach and Engagement Core

Outreach, Recruitment and Engagement Core

The ORE Core promotes outreach and education in the community in order to facilitate research recruitment into the ADRC and its supported projects, with a particular focus on the enfranchisement of clinically underserved groups in our region.

Research Education Core

Research Education Component

The REC’s goal is to develop future leaders in AD+ADRD research by providing early-career exposure to AD+ADRD research, delivering broad cross-campus research education, and annually selecting REC Scholars for focused research mentorship and funding.