Cellular Pathology

Dr. Axtman’s research focuses on the synthesis of small molecules that selectively modulate proteins implicated in disease-propagating pathways. She works at the interface of chemistry and biology. She is funded to develop reagents to validate novel therapeutic hypotheses related to AD.

The Coleman lab studies how modifiable risk factors for AD promote its cellular and behavioral pathology. By using mouse models and human tissue, we attempt to identify novel diagnostic and therapeutic targets for AD. Studies focus on underlying cellular and molecular pathology that promote AD pathogenesis and progression

REC Scholar Project: Targeting autophagy to monitor age-related cognitive decline and the dementia risk

Professor Lopez is an associate professor in the Biological and Biomedical Sciences Department at North Carolina Central University. Her research interests include regulation of the hepatic LDL receptor and PCSK9 and the role of hypothyroidism in Alzheimer’s disease and breast cancer.

Dr. Smith’s work focuses on understanding molecular mechanisms implicated in chronic human disease using bioinformatics tools.